Bronchodilator effect of inhaled ipratropium bromide in wheezy toddlers.
نویسندگان
چکیده
smoking mothers are thinner and their babies are thinner too, but even accepting the limitations of correction for this effect, the growth-retarding effect of smoking on the fetus is hardly affected by this correction. A similar conclusion was derived from Cardiff Birth Survey data, in a community study on smoking and pregnancy.8 We postulate from our data and from other data already reported, that the growth-retarding effect of maternal smoking on the infant is a complex multifactorial one. It is clear that efforts should be intensified to prevent expectant mothers smoking as there is evidence that there may be long-term effects on children's learning ability later in childhood,9 and we and Davies et al.6 have found a reduction in head circumference in the infants of smoking mothers.
منابع مشابه
Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials
BACKGROUND Asthmatics treated with long-acting beta-agonists have a reduced bronchodilator response to moderate doses of inhaled short acting beta-agonists during acute bronchoconstriction. It is not known if the response to higher doses of nebulised beta-agonists or other bronchodilators is impaired. We assessed the effect of long-acting beta-agonist treatment on the response to 5 mg nebulised...
متن کاملIpratropium bromide and airways function in wheezy infants.
The airway response to nebulised ipratropium bromide was studied in 17 chronically or recurrently wheezy infants aged 4-15 months. The peripheral airway response was assessed by the change in maximum flow at functional residual capacity (Vmax FRC) and the upper and central airway response by the change in specific airways resistance. The significant reduction in specific airways resistance afte...
متن کاملEffect of four weeks' high dose ipratropium bromide
In a randomised, double blind crossover study the effect of high dose ipratropium bromide (200 pg three times daily given by metered dose inhaler for four weeks) on lung mucociliary clearance and on the wet weight and mean apparent viscosity of sputum was compared with that of placebo. Six smokers, six ex-smokers, and three non-smokers (12 men and three women, median age 60 years) were studied....
متن کاملCOMPARISON OF THE ACUTE BRONCHO DILATING EFFECTS OF INHALED IPRATROPIUM BROMIDE AND SALBUTAMOL IN PATIENTS WI TH CHRONIC OBSTRUCTIVE PULMONARY DISE ASE
Forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (FEV 1) and forced vital capacity (PVC). Ipratropium bromide produced a significantly greater improvement than salbutamol in both FEV1 and FVC at 15,60 and 180 minutes afte...
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In the last 2 decades, anticholinergic agents have been generally regarded as the first-choice bronchodilator therapy in the routine management of stable chronic obstructive pulmonary disease (COPD) and, to a lesser extent, asthma. Anticholinergics are particularly important bronchodilators in COPD, because the vagal tone appears to be the only reversible component of airflow limitation in COPD...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 56 9 شماره
صفحات -
تاریخ انتشار 1981